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Publications
Restoring activity in the thalamic reticular nucleus improves sleep architecture and reduces A? accumulation in mice
Corticothalamic network dysfunction and Alzheimer's disease
Alzheimer's disease is accompanied by diverse cognitive and behavioral deficits.
The corticothalamic network may be a master regulator of multiple domains in AD.
Early deficits in sleep may increase Abeta and susceptibility to AD.
Investigation of the corticothalamic network in AD may provide new insight to disease.
Expression of class II histone deacetylases in two mouse models of temporal lobe epilepsy.
Rapid changes in expression of class I and IV histone deacetylases during epileptogenesis in mouse models of temporal lobe epilepsy.
Pronounced dynamic changes of class I and IV HDACs in the hippocampus during epileptogenesis. Decreased expression of HDACs during the status epilepticus coincides with a time window of increased protein expression. Increased HDAC expression during recovery from status epilepticus coincides with the phase of epileptogenesis.
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